Glossary
Leukocyte- and platelet-rich fibrin (L-PRF)
L-PRF is the original solid platelet-rich fibrin, produced by centrifuging blood without anticoagulant so that a fibrin clot forms during the spin. It is harvested as a solid membrane rather than drawn as a liquid.
Figure
The original protocol
Figure. L-PRF is reported at 408 g at the clot for twelve minutes, which corresponds to 653 g at the bottom of the tube and 326 g at the top. An unqualified RCF value is close to meaningless, and this is why.
In practice
The original L-PRF protocol is reported as 408 g at the clot for 12 minutes, which corresponds to 653 g at the bottom of the tube and 326 g at the top. Those three figures describe the same spin, which is why an unqualified RCF value is close to meaningless.
See also
- Platelet-rich fibrin (PRF)PRF is a platelet concentrate produced without anticoagulant, so the blood clots during centrifugation and forms a fibrin matrix.
- Advanced PRF (A-PRF)A-PRF is a solid platelet-rich fibrin produced with reduced force and increased time relative to the original L-PRF protocol, with the aim of raising leukocyte content and distributing cells more evenly through the clot.
- Relative centrifugal force (RCF)RCF is the force a centrifuge applies to a sample, expressed as a multiple of Earth's gravity and written as g.