regenmedtools
Series

Quality and reproducibility

The quality series is the applied version of a documented problem: protocol reporting in this field is not standardised, and two clinics running the same published protocol routinely get different results. Twelve bulletins on verifying your own machine, documenting a protocol properly, and knowing when one cannot be transferred at all.

Figure

Why the same protocol gives different results

DENSITY ยท KG PER CUBIC METRE Plasma 1,025 Platelets 1,040 to 1,060 Leukocytes 1,050 to 1,085 Erythrocytes 1,090 to 1,100 Denser fractions sediment faster. That gap is the entire basis of separation.

Figure. The physics is identical in every clinic. The rotor radius, the tube, the anticoagulant, and the draw are not. A systematic review of the PRF literature found 29 protocols across 16 machines and no standardisation in how any of it is reported.

Bulletins

12 · 0 published
RMT‑79Why two clinics get different results from the same protocolIn preparation
RMT‑80Documenting a protocol properlyIn preparation
RMT‑81Verifying your machine's actual RCFIn preparation
RMT‑82Platelet count verification, before and afterIn preparation
RMT‑83Batch consistencyIn preparation
RMT‑84Operator variationIn preparation
RMT‑85Staff training and competencyIn preparation
RMT‑86Building a protocol libraryIn preparation
RMT‑87What to record for every procedureIn preparation
RMT‑88Reading a study's methods sectionIn preparation
RMT‑89When a protocol cannot be transferredIn preparation
RMT‑90The reproducibility checklistIn preparation