Glossary
Platelet-rich fibrin (PRF)
PRF is a platelet concentrate produced without anticoagulant, so the blood clots during centrifugation and forms a fibrin matrix. It is described as a second-generation platelet concentrate and comes in solid and liquid forms.
Figure
PRF, without anticoagulant
Figure. PRF clots during the spin, which is why no anticoagulant is used and why timing becomes an operational constraint on room layout rather than merely on protocol.
In practice
Because PRF requires no anticoagulant, timing matters: the blood must reach the centrifuge quickly. This is an operational constraint on room layout, not just on protocol.
See also
- Injectable PRF (i-PRF)i-PRF is a liquid form of platelet-rich fibrin prepared at low centrifugal force and short duration, which leaves it injectable before it clots.
- Leukocyte- and platelet-rich fibrin (L-PRF)L-PRF is the original solid platelet-rich fibrin, produced by centrifuging blood without anticoagulant so that a fibrin clot forms during the spin.
- Advanced PRF (A-PRF)A-PRF is a solid platelet-rich fibrin produced with reduced force and increased time relative to the original L-PRF protocol, with the aim of raising leukocyte content and distributing cells more evenly through the clot.