Glossary

Leukocyte

A leukocyte is a white blood cell. Leukocytes make up roughly one percent of blood and concentrate in the buffy coat alongside platelets. Whether they are kept or excluded defines leukocyte-rich and leukocyte-poor PRP.

Figure

Where leukocytes sit

DENSITY · KG PER CUBIC METRE Plasma 1,025 Platelets 1,040 to 1,060 Leukocytes 1,050 to 1,085 Erythrocytes 1,090 to 1,100 Denser fractions sediment faster. That gap is the entire basis of separation.

Figure. Leukocyte density falls between that of platelets and erythrocytes, which is why they co-locate with platelets in the buffy coat and are difficult to separate from them. That difficulty is the whole leukocyte-rich versus leukocyte-poor question.

In practice

Leukocyte density sits between that of erythrocytes and platelets, which is why they co-locate with platelets in the buffy coat and are difficult to separate from them.

See also