Glossary

Leukocyte-rich PRP (L-PRP)

Leukocyte-rich PRP retains the white cells that concentrate alongside platelets in the buffy coat. It is associated with a stronger inflammatory signal, which some protocols seek and others deliberately avoid.

Figure

Drawing wide

PLASMA about 55% of the column BUFFY COAT platelets and leukocytes. about 1%. Drawn to scale. This is the whole target. RED CELLS densest fraction. sediments first. CENTRIFUGAL FORCE

Figure. Leukocyte-rich PRP retains the white cells that concentrate alongside platelets. Two clinics can both be truthfully offering PRP and be delivering materially different preparations, and the draw is where that divergence happens.

In practice

Leukocyte content is one of the largest sources of variation between products described simply as PRP. Two clinics can both be truthfully offering PRP and be delivering materially different preparations.

See also