Glossary

Concentrated PRF (C-PRF)

C-PRF is a platelet-rich fibrin variant in which the upper plasma layer is fractionated to isolate the fraction with the highest platelet and leukocyte concentration, rather than using the whole liquid layer.

Figure

Fractionating the plasma layer

PLASMA about 55% of the column BUFFY COAT platelets and leukocytes. about 1%. Drawn to scale. This is the whole target. RED CELLS densest fraction. sediments first. CENTRIFUGAL FORCE

Figure. C-PRF isolates the fraction of the upper layer with the highest platelet and leukocyte concentration rather than using the whole liquid layer. It is a pipetting technique, and it is therefore more sensitive to operator skill than most protocols.

In practice

C-PRF is a preparation technique rather than a machine capability. It requires careful, layered pipetting and is therefore more sensitive to operator skill than most protocols.

See also