---
title: Platelet-rich fibrin (PRF)
url: https://regenmedtools.com/glossary/prf/
type: glossary
primaryQuery: platelet rich fibrin
---

# Platelet-rich fibrin (PRF)

PRF is a platelet concentrate produced without anticoagulant, so the blood clots during centrifugation and forms a fibrin matrix. It is described as a second-generation platelet concentrate and comes in solid and liquid forms.

Because PRF requires no anticoagulant, timing matters: the blood must reach the centrifuge quickly. This is an operational constraint on room layout, not just on protocol.


## Related
- [i-prf](https://regenmedtools.com/glossary/i-prf/)
- [l-prf](https://regenmedtools.com/glossary/l-prf/)
- [a-prf](https://regenmedtools.com/glossary/a-prf/)