---
title: Leukocyte- and platelet-rich fibrin (L-PRF)
url: https://regenmedtools.com/glossary/l-prf/
type: glossary
primaryQuery: l-prf
---

# Leukocyte- and platelet-rich fibrin (L-PRF)

L-PRF is the original solid platelet-rich fibrin, produced by centrifuging blood without anticoagulant so that a fibrin clot forms during the spin. It is harvested as a solid membrane rather than drawn as a liquid.

The original L-PRF protocol is reported as 408 g at the clot for 12 minutes, which corresponds to 653 g at the bottom of the tube and 326 g at the top. Those three figures describe the same spin, which is why an unqualified RCF value is close to meaningless.


## Related
- [prf](https://regenmedtools.com/glossary/prf/)
- [a-prf](https://regenmedtools.com/glossary/a-prf/)
- [rcf](https://regenmedtools.com/glossary/rcf/)