---
title: Concentrated PRF (C-PRF)
url: https://regenmedtools.com/glossary/c-prf/
type: glossary
primaryQuery: c-prf concentrated platelet rich fibrin
---

# Concentrated PRF (C-PRF)

C-PRF is a platelet-rich fibrin variant in which the upper plasma layer is fractionated to isolate the fraction with the highest platelet and leukocyte concentration, rather than using the whole liquid layer.

C-PRF is a preparation technique rather than a machine capability. It requires careful, layered pipetting and is therefore more sensitive to operator skill than most protocols.


## Related
- [prf](https://regenmedtools.com/glossary/prf/)
- [i-prf](https://regenmedtools.com/glossary/i-prf/)
- [buffy-coat](https://regenmedtools.com/glossary/buffy-coat/)