--- title: Advanced PRF (A-PRF) url: https://regenmedtools.com/glossary/a-prf/ type: glossary primaryQuery: a-prf advanced platelet rich fibrin --- # Advanced PRF (A-PRF) A-PRF is a solid platelet-rich fibrin produced with reduced force and increased time relative to the original L-PRF protocol, with the aim of raising leukocyte content and distributing cells more evenly through the clot. A-PRF, like L-PRF, requires a horizontal rotor. That single requirement excludes a large share of the compact benchtop centrifuges marketed for PRP work. ## Related - [prf](https://regenmedtools.com/glossary/prf/) - [l-prf](https://regenmedtools.com/glossary/l-prf/) - [horizontal-centrifugation](https://regenmedtools.com/glossary/horizontal-centrifugation/)